SOURCE

<div class="box">
    <div class="item1">1</div>
<div class="item2">2</div>
<div class="item3">3</div>
<div class="item4">4</div>
<div class="item5">5</div>
</div>

.box {
    display: flex;
    justify-content: space-between;
    align-items: center;
    flex-wrap: wrap;
}

.box > * {
    background: blue;
    height: 200px;
    width: 100px;
}

.item1, .item2, .item3 {
    width: 30%;
}
.item2 {
    height: 300px;
}

.item3 {
    height: 100px;
}